IL-23R–activated STAT3/STAT4 is essential for Th1/Th17-mediated CNS autoimmunity
نویسندگان
چکیده
منابع مشابه
IL-23R-activated STAT3/STAT4 is essential for Th1/Th17-mediated CNS autoimmunity.
The factors that promote the differentiation of pathogenic T cells in autoimmune diseases are poorly defined. Use of genetically modified mice has provided insight into molecules necessary for the development of autoimmunity, but the sum of the data has led to contradictory observations based on what is currently known about specific molecules in specific signaling pathways. To define the minim...
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ژورنال
عنوان ژورنال: JCI Insight
سال: 2017
ISSN: 2379-3708
DOI: 10.1172/jci.insight.91663